Dm. Rector et al., VENTRAL MEDULLARY SURFACE-ACTIVITY DURING SLEEP, WAKING, AND ANESTHETIC STATES IN THE GOAT, American journal of physiology. Regulatory, integrative and comparative physiology, 36(4), 1994, pp. 180001154-180001160
We examined activity, measured as changes in reflected light, from the
surface of a rostral ventral medullary area that is involved in cardi
orespiratory control. We collected images during sleep and waking stat
es and during halothane anesthesia in live adult unrestrained goats. D
uring quiet sleep, overall activity increased and overall variability
decreased compared with waking levels, whereas rapid eye movement slee
p increased variability, and average activity decreased to near-waking
levels. Distinct regions of activation and suppression appeared durin
g sleep states. Deep anesthesia decreased activity and minimized varia
tion. We speculate that alterations in rostral ventral medullary surfa
ce activity may play a role in state-dependent changes in cardiorespir
atory control mechanisms.