IMPROVEMENT OF ABNORMAL SACCADIC EYE-MOVEMENTS IN HUNTINGTONS-DISEASEBY SULPIRIDE - A CASE-STUDY

Citation
Ma. Reveley et al., IMPROVEMENT OF ABNORMAL SACCADIC EYE-MOVEMENTS IN HUNTINGTONS-DISEASEBY SULPIRIDE - A CASE-STUDY, J PSYCHOPH, 8(4), 1994, pp. 262-265
Citations number
14
Categorie Soggetti
Pharmacology & Pharmacy",Neurosciences,"Pharmacology & Pharmacy",Neurosciences
Journal title
JOURNAL OF PSYCHOPHARMACOLOGY
ISSN journal
02698811 → ACNP
Volume
8
Issue
4
Year of publication
1994
Pages
262 - 265
Database
ISI
SICI code
0269-8811(1994)8:4<262:IOASEI>2.0.ZU;2-6
Abstract
Sulpiride treatment improved both the abnormal asymmetric saccadic eye movements (SEM) and the abnormal involuntary movements (AIMs) in a pa tient with Huntington's disease (HD). However, sulpiride corrected the abnormalities of SEM in the right, but not the left, hemi-field and t he degeneration of the left striatal tissue was greater as visualised by the magnetic resonance imaging (MRI) scan.