In 1924 Josef Gerstmann described <<finger agnosia>>, an apparently hi
therto unrecognized behavioral deficit appearing as a consequence of c
erebral disease. In this and subsequent papers, he called attention to
the frequent association of finger agnosia with right-left disorienta
tion, acalculia, and agraphia. His observations were soon confirmed by
other investigators, and the tetrad of sympstoms has come to be known
as the Gerstmann's syndrome. For years neuropsychologists have consid
ered this syndrome as diagnostic of disease in the dominant parietal l
obe. However considerable attention has been devoted to the neuropsych
ological significance of the syndrome. Several authors have questioned
its existence and have tried to cast doubt on its diagnostic value an
d theoretical importance. This paper provides the clinical-phenomenolo
gic definition of the syndrome and its associated features related wit
h its neuropathological significance and reviews the subject in the li
ght of present day reports. On this basis, the neuropsychological sign
ificance of the syndrome is assessed and some persisting questions are
considered.