PREPARATION AND UTILITY OF 5-BETA-D-RIBOFURANOSYL-1H-TETRAZOLE AS A KEY SYNTHON FOR C-NUCLEOSIDE SYNTHESIS

Authors
KOBE J PRHAVC M HOHNJEC M TOWNSEND LB
Citation
J. Kobe et al., PREPARATION AND UTILITY OF 5-BETA-D-RIBOFURANOSYL-1H-TETRAZOLE AS A KEY SYNTHON FOR C-NUCLEOSIDE SYNTHESIS, Nucleosides & nucleotides, 13(10), 1994, pp. 2209-2244
Citations number
42
Categorie Soggetti
Biology
Journal title
Nucleosides & nucleotides → ACNP
ISSN journal
07328311
Volume
13
Issue
10
Year of publication
1994
Pages
2209 - 2244
Database
ISI
SICI code
0732-8311(1994)13:10<2209:PAUO5A>2.0.ZU;2-X
Abstract
A synthesis of 5-beta-D-ribofuranosyl-1H-tetrazole (2) and 5-beta-D-ri bo-furanosyl-1,3,4-oxadiazole-2(3H)-one (9) derivatives is described. Ring transformations of 2 have been investigated in an effort to estab lish the stability of this synthon for further use in dipolar cycloadd ition reactions.