DESTOMBES-ROSAI-DORFMANS-SYNDROME - 2 UNU SUAL CASES

Two cases of Destombes Rosai Dorfman's syndrome are presented. Diagnos is was performed by superficial lymph node biopsy. The first case conc erned a nine and half years old girl with cervical adenopathy who deve loped a compressive mediastinal adenopathy responsible for a right low er lobe atelectasis. Because of local lung suppuration a lobectomy had to be performed The second case concerned a fourteen years old boy wi th recurrent fever, diffuse superficial lymph nodes and erythematous s kin rash. The two patients showed clinical and biological inflammatory symptoms without any immunodeficiency. No aetiological agent could be identified. Antibiotics and corticoids had no effect but the Two pati ents recovered (after 18 months follow up in case 2). These two partic ular cases confirm the clinical course heterogeneicity of the syndrome which requires histological diagnosis.