The laser Doppler flowmeter, an instrument highly sensitive to changes
in blood flow velocity in the dermal microvascular bed, was used to e
xamine a sympathetic vasomotor response (SVR) in 40 patients with late
ral epicondylitis. There was a significant association between the abs
ence of a normal SVR in the skin overlying the affected enthesis compa
red with the unaffected contralateral epicondyle (P<0.01). These resul
ts suggest that local dysfunction of the sympathetic nervous system ma
y be associated with the pathogenesis of anatomically discrete pain in
the enthesopathy of epicondylitis.