B. Cassinat et Mh. Nicolas, COMPARISON OF ANTIBIOTIC COMBINATIONS AGAINST PENICILLIN-RESISTANT PNEUMOCOCCI, Journal of antimicrobial chemotherapy, 34(5), 1994, pp. 785-790
The isolation rate of penicillin resistant pneumococci is increasing i
n France. To date, cefotaxime and ceftriaxone are the two drugs recomm
ended for the treatment of severe infections and oral third generation
cephalosporins are frequently employed for the treatment of non-invas
ive pneumococcal diseases. In this study, we determined the bacteriost
atic activity of 21 antibiotic combinations against 13 clinical isolat
es of Streptococcus pneumoniae with MICs greater than or equal to 0.1
mg/L penicillin and 13 strains that were susceptible.