ESTIMATION OF THE PORE-SIZE AND CHARGE-DENSITY IN HUMAN CADAVER SKIN

Streaming potential and the cation transport number were measured in h uman cadaver skin. The transport number was used to estimate the charg e density in aqueous pores of skin using both Donnan equilibrium and L angmuir adsorption isotherm. A microscopic model was employed to evalu ate the pore radius from the streaming potential and charge density da ta. The capillary pore model was extended to account for any distribut ion of pore size, and applied particularly to the gaussian distributio n. The mean radius of the distribution appeared to be slightly less th an that of the single pore model. In both cases the radii were ca. 20 nm.