The efficacy and tolerability of high-dose neutrotrophic drug cerebrol
ysin was studied in 20 patients with vascular dementia diagnosed by cr
iteria NINDS-AIREN and DSM-IV. The drug was well tolerated, affected p
ositively cognitive function, especially neurodynamic processes. EEG f
eatured aftertreatment intensification of rapid rhythms power and a de
crease in delta-activity spectrum. The highest effect of cerebrolysin
was achieved in patients with mild cognitive defects.