ARTEMISININ PRODUCTION BY TRANSFORMED ROOTS OF ARTEMISIA-ANNUA

Authors
WEATHERS PJ CHEETHAM RD FOLLANSBEE E TEOH K
Citation
Pj. Weathers et al., ARTEMISININ PRODUCTION BY TRANSFORMED ROOTS OF ARTEMISIA-ANNUA, Biotechnology letters, 16(12), 1994, pp. 1281-1286
Citations number
19
Categorie Soggetti
Biothechnology & Applied Migrobiology
Journal title
Biotechnology letters → ACNP
ISSN journal
01415492
Volume
16
Issue
12
Year of publication
1994
Pages
1281 - 1286
Database
ISI
SICI code
0141-5492(1994)16:12<1281:APBTRO>2.0.ZU;2-Z
Abstract
Transformed root cultures of several strains of Artemisia annua were o btained by infection with Agrobacterium rhizogenes ATCC 15834. Product ion of artemisinin, measured by HPLC, ranged from 0-0.42 % of dry weig ht (DW) in 10 different clones. Artemistene, artemisinic acid, and art eannuin B were also measured. Comparisons to literature reports sugges t that the commercial production of artemisinic compounds using transf ormed roots is feasible.