DOUBLE KINETIC RESOLUTION OF (+ -) ETHYL 4-CHLORO-3-0-ACETYL BUTANOATE/

Authors
THAKKAR NV BANERJI AA BEVINAKATTI HS
Citation
Nv. Thakkar et al., DOUBLE KINETIC RESOLUTION OF (+ -) ETHYL 4-CHLORO-3-0-ACETYL BUTANOATE/, Biotechnology letters, 16(12), 1994, pp. 1299-1302
Citations number
5
Categorie Soggetti
Biothechnology & Applied Migrobiology
Journal title
Biotechnology letters → ACNP
ISSN journal
01415492
Volume
16
Issue
12
Year of publication
1994
Pages
1299 - 1302
Database
ISI
SICI code
0141-5492(1994)16:12<1299:DKRO(->2.0.ZU;2-R
Abstract
Single pot double kinetic resolution of (+/-) ethyl 4-chloro-3-O-acety l butanoate 1 by transesterification with n-butanol in diisopropyl eth er using the enzyme Candida Cylindracea Lipase (CCL) is investigated. This technique is found to give products with better optical purity.