DETECTION OF CLENBUTEROL RESIDUES IN HAIR

Citation
A. Adam et al., DETECTION OF CLENBUTEROL RESIDUES IN HAIR, Analyst, 119(12), 1994, pp. 2663-2666
Citations number
21
Categorie Soggetti
Chemistry Analytical
Journal title
ISSN journal
00032654
Volume
119
Issue
12
Year of publication
1994
Pages
2663 - 2666
Database
ISI
SICI code
0003-2654(1994)119:12<2663:DOCRIH>2.0.ZU;2-F
Abstract
Sixty rats were grown in the presence of 10 (n = 30) and 100 (n = 30) pg kg(-1) body mass of clenbuterol for a period of 10 d, An immunoextr action step coupled with a competitive enzyme immunoassay allowed the quantification of clenbuterol in hair upon 20 (10 mu g kg(-1)) and 30 d (100 mu g kg(-1)) after the last dose. This accumulation in hair con trasts with the rapid clearance in tissues. The nature of the immunore active material was confirmed by mass spectrometry.