CHEMOKINES, LEUKOCYTE TRAFFICKING, AND INFLAMMATION

The relatively recent appreciation of a new class of cytokines, the ch emokines, has done much to enhance our understanding of the extracellu lar signals involved in the movement of various populations of white b lood cells. Investigation of the molecular underpinnings of chemokine function and their involvement in inflammatory processes of all kinds is beginning to yield information about the mechanisms of pathogenesis of a number of conditions, as well as providing hope for new therapeu tic insights.