REVIEW OF THE EMBRYOLOGIC DEVELOPMENT OF THE PITUITARY-GLAND AND REPORT OF A CASE OF HYPOPHYSEAL DUPLICATION DETECTED BY MRI

Authors
KOLLIAS SS BALL WS PRENGER EC
Citation
Ss. Kollias et al., REVIEW OF THE EMBRYOLOGIC DEVELOPMENT OF THE PITUITARY-GLAND AND REPORT OF A CASE OF HYPOPHYSEAL DUPLICATION DETECTED BY MRI, Neuroradiology, 37(1), 1995, pp. 3-12
Citations number
34
Categorie Soggetti
Radiology,Nuclear Medicine & Medical Imaging",Neurosciences
Journal title
Neuroradiology → ACNP
ISSN journal
00283940
Volume
37
Issue
1
Year of publication
1995
Pages
3 - 12
Database
ISI
SICI code
0028-3940(1995)37:1<3:ROTEDO>2.0.ZU;2-F
Abstract
We describe the clinical manifestations, associated abnormalities, MRI appearances and pathologic significance of a case of hypophyseal dupl ication. A 16-year-old girl presented with delayed sexual development and history of midline craniofacial anomalies. MRI revealed paired inf undibula extending inferiorly to two small pituitary glands, a midline hypothalamic mass, and a midline cleft in the basisphenoid. Twelve ca ses of pituitary duplication have previously been described. The sugge sted pathogenesis is duplication of the prechordal plate and anterior end of the notochord during early embryologic development.