This article reviews the evolutionary origins and functions of the cap
acity for anxiety, and relevant clinical and research issues. Normal a
nxiety is an emotion that helps organisms defend against a wide variet
y of threats. There is a general capacity for normal defensive arousal
, and subtypes of normal anxiety protect against particular kinds of t
hreats. These normal subtypes correspond somewhat to mild forms of var
ious anxiety disorders. Anxiety disorders arise from dysregulation of
normal defensive responses, raising the possibility of a hypophobic di
sorder (too little anxiety). If a drug were discovered that abolished
all defensive anxiety, it could do harm as well as good. Factors that
have shaped anxiety-regulation mechanisms can explain prepotent and pr
epared tendencies to associate anxiety more quickly with certain cues
than with others. These tendencies lead to excess fear of largely arch
aic dangers, like snakes, and too little fear of new threats, like car
s. An understanding of the evolutionary origins, functions, and mechan
isms of anxiety suggests new questions about anxiety disorders.