Jl. Truelle et al., MOVEMENT DISTURBANCES FOLLOWING FRONTAL-LOBE LESIONS - QUALITATIVE-ANALYSIS OF GESTURE AND MOTOR PROGRAMMING, Neuropsychiatry, neuropsychology, and behavioral neurology, 8(1), 1995, pp. 14-19
The goal of this systematic examination of Luria's hypothesis regardin
g frontal lobe functions was to identify the types of gesture and moto
r programming errors most closely associated with lesions in different
areas of the frontal lobes. A test protocol based on Luria's examinat
ion techniques was given to 75 patients with isolated frontal involvem
ent. This protocol identified the three most prominent types of errors
: simplification, deautomatization, and disinhibition. Simplification
was linked with prefrontal lesions (p < .02), deautomatization was ass
ociated with premotor lesions (p <.001), and disinhibition tended to b
e linked with lesions involving the orbitomedial region (p < .001).