THE HYPOTONIC EFFECT OF INTRANASAL AND INTRAVENOUS GLUCAGON IN GASTROINTESTINAL RADIOLOGY

In the present study, following a double-blind, double placebo protoco l vs. placebo, we compared the hypotonic effect of intranasal and intr avenous glucagon during a double-contrast barium meal examination of t he stomach. We found a statistically significant difference between pl acebo and intranasal or intravenous glucagon in inducing gastric hypom otility, with no significant differences between IN and IV glucagon. T he intranasal administration of glucagon has the advantage of being no ninvasive and well tolerated by the patients, and might be a valuable aid in upper gastrointestinal examination as well as in CT scan or mag netic resonance imaging of the abdomen.