In this paper, we analyzed jet-lag syndrome, a transient circadian rhy
thm sleep disorder produced by an abrupt desynchronization between the
internal clock and environmental cues. Jet-Lag is an entirely self-in
flicted condition resulting from transmeridian air travel. As determin
ant factors of jet-lag circadian rhythmicity, number of time zones tra
versed, velocity and direction of travel, and capacity of adaptation t
o the new time zone are considered. Likewise, diagnostic criteria, cli
nical symptoms and polysomnographic features of jet-lag are also descr
ibed. Finally, we conclude by outlining some recommendations for clini
cal intervention used to alleviate jet-lag.