A magnetic resonance imaging sequence, combining fat and flow suppress
ion with T-2 weighting, has been used to produce high conspicuity imag
es of the median nerve within the carpal tunnel. Standard maximum inte
nsity projection techniques were then used to produce three-dimensiona
l (3D) reconstructions of the nerve. Comparison of 3D projections with
the wrist in a neutral position and wrist flexed at 45 degrees depict
ed changes in the shape and course of the median nerve through the car
pal tunnel of normal volunteers. In some cases of carpal tunnel syndro
me evidence of a localized compression was observed. A 3D image of a n
erve may help in the diagnosis of peripheral neuropathy and be an aid
to surgery of or near major nerves.