THE EFFECT OF CROMOLYN SODIUM AND NEDOCROMIL SODIUM ADMINISTERED BY APRESSURIZED AEROSOL WITH A SPACER DEVICE ON EXERCISE-INDUCED ASTHMA IN CHILDREN

Authors
DEBENEDICTIS FM TUTERI G NICCOLI A MEZZETTI D ROSSI L BRUNI L
Citation
Fm. Debenedictis et al., THE EFFECT OF CROMOLYN SODIUM AND NEDOCROMIL SODIUM ADMINISTERED BY APRESSURIZED AEROSOL WITH A SPACER DEVICE ON EXERCISE-INDUCED ASTHMA IN CHILDREN, Mediators of inflammation, 3, 1994, pp. 35-37
Citations number
19
Categorie Soggetti
Cell Biology",Biology
Journal title
Mediators of inflammation → ACNP
ISSN journal
09629351
Volume
3
Year of publication
1994
Supplement
1
Pages
35 - 37
Database
ISI
SICI code
0962-9351(1994)3:<35:TEOCSA>2.0.ZU;2-K
Abstract
To compare the effectiveness of cromolyn sodium (CS) (10 mg) and nedoc romil sodium (NS) (4 mg) administered by a metered dose inhaler (MDI) with a spacer device in preventing exercise-induced asthma (EIA), eigh t asthmatic children with EIA were studied in randomized double-blind, cross-over, placebo-controlled study. CS and NS provided significant, comparable protection from EIA and both were better than placebo. We conclude that CS and NS administered by a pressurized aerosol with a s pacer device provide equal protection against EIA in children.