STRATEGIES FOR PRENATAL HLA TYPING FOR POTENTIAL CORD-BLOOD DONOR EVALUATION

Authors
POLLACK MS GRANT GJ
Citation
Ms. Pollack et Gj. Grant, STRATEGIES FOR PRENATAL HLA TYPING FOR POTENTIAL CORD-BLOOD DONOR EVALUATION, Blood cells, 20(2-3), 1994, pp. 310-315
Citations number
11
Categorie Soggetti
Hematology
Journal title
Blood cells → ACNP
ISSN journal
03404684
Volume
20
Issue
2-3
Year of publication
1994
Pages
310 - 315
Database
ISI
SICI code
0340-4684(1994)20:2-3<310:SFPHTF>2.0.ZU;2-G
Abstract
The reasons for prenatal HLA typing for potential cord blood stem cell donor evaluation are reviewed and the strategies for doing so are sum marized. Cultured fetal cells are class I HLA typed by modified serolo gical techniques. When indicated, the fetal cells are also class II HL A typed by one or another DNA typing method. The same procedures can b e used for the prenatal identification of a potential donor for an aff ected fetus.