CHROMOSOMAL LOCALIZATION OF HUMAN, RAT, AND MOUSE PROTEIN PHOSPHATASETYPE 1-BETA CATALYTIC SUBUNIT GENES (PPP1CB) BY FLUORESCENCE IN-SITU HYBRIDIZATION

Authors
SAADAT M KAKINOKI Y MIZUNO Y KIKUCHI K YOSHIDA MC
Citation
M. Saadat et al., CHROMOSOMAL LOCALIZATION OF HUMAN, RAT, AND MOUSE PROTEIN PHOSPHATASETYPE 1-BETA CATALYTIC SUBUNIT GENES (PPP1CB) BY FLUORESCENCE IN-SITU HYBRIDIZATION, Idengaku Zasshi, 69(6), 1994, pp. 697-700
Citations number
12
Categorie Soggetti
Genetics & Heredity
Journal title
Idengaku Zasshi → ACNP
ISSN journal
0021504X
Volume
69
Issue
6
Year of publication
1994
Pages
697 - 700
Database
ISI
SICI code
0021-504X(1994)69:6<697:CLOHRA>2.0.ZU;2-4
Abstract
Using fluorescent in situ hybridization (FISH) method, gene encoding t he catalytic subunit of protein phosphatase type 1 beta (PPP1CB) in hu man and its corresponding gene in rat (PP1 delta) and mouse (dis2m2) w ere mapped to human 2p23, rat 6q21-q23, and mouse 12D, respectively. T hese results indicate that PPP1CB is a member of conserved syntenic gr oup. It is shown that the genes encoding catalytic subunit of protein phosphatase type 1 family (PP1 alpha, PP1 beta, and PP1 gamma in human and those corresponding genes in rat and mouse), in spite of their hi gh identity, are located to different chromosomes in these three speci es.