NEW SUPPRESSOR GENES WHICH REGULATE THE C ELL-CYCLE

Authors
Citation
B. Grandchamp, NEW SUPPRESSOR GENES WHICH REGULATE THE C ELL-CYCLE, Annales de genetique, 37(3), 1994, pp. 117-120
Citations number
10
Categorie Soggetti
Genetics & Heredity
Journal title
ISSN journal
00033995
Volume
37
Issue
3
Year of publication
1994
Pages
117 - 120
Database
ISI
SICI code
0003-3995(1994)37:3<117:NSGWRT>2.0.ZU;2-1
Abstract
Eukaryotic cell cycle progression is governed by multiple cyclin and c yclin-dependent kinases interactions that are in turn regulated by mul tiple factors. Recently, inhibitors of cyclin/cyclin-dependent kinases activities have been characterized and their genes have been cloned. Alterations of some these genes may play a major in tumor initiation o r progression.