NEW MODIFIED SUBSTRATES FOR DISCRIMINATING BETWEEN HUMAN DNA POLYMERASE-ALPHA AND POLYMERASE-EPSILON

Authors
JASKO MV SEMIZAROV DG VICTOROVA LS MOZZHERIN DJ KRAYEVSKY AA KUKHANOVA MK
Citation
Mv. Jasko et al., NEW MODIFIED SUBSTRATES FOR DISCRIMINATING BETWEEN HUMAN DNA POLYMERASE-ALPHA AND POLYMERASE-EPSILON, FEBS letters, 357(1), 1995, pp. 23-26
Citations number
15
Categorie Soggetti
Biophysics,Biology
Journal title
FEBS letters → ACNP
ISSN journal
00145793
Volume
357
Issue
1
Year of publication
1995
Pages
23 - 26
Database
ISI
SICI code
0014-5793(1995)357:1<23:NMSFDB>2.0.ZU;2-M
Abstract
Two 2'-deoxynucleoside -alpha-methylenephosphonyl-beta,gamma-diphospha tes mere synthesized, They mere incorporated into the DNA chain by DNA polymerase cu from human placenta, Meanwhile, they were not recognize d by DNA polymerases epsilon and beta of the same origin as well as by reverse transcriptases from human immunodeficiency virus and avian my eloblastosis virus.