AN UNUSUAL ASSOCIATION OF FIBROMYXOMA AND OSTEOMA OF THE FRONTAL-SINUS - THE BENIGN FIBROMYXO-OSTEOMA

Myxomas, and especially fibromyxomas of the head and neck are rare but when occurring are usually located in the mandibule. Here we present the case of a 24-year old man with an unusual mesenchymal tumor in the frontal sinus. Microscopic and histomorphological aspects demonstrate d a benign tumor with biphasic differentiation (a myxoid and an osteoi d part). The tumor was therefore classified as fibromyxo-osteoma. The association of two different tumors is not probable because of the ext remely narrow topographic link between soft tissue and osteoid tumor p arts. Other arguments against a perifocal myxoid reaction of the osteo ma are that myxoid degeneration of osteomas is unknown and that approp riate immunohistochemical methods were able to show a relatively high proliferation activity of the spindle-shaped cells in the myxoid tissu e. Therapy consisted of complete resection of the well-delimited tumor . The patient has remained free of any recurrence 2 years after primar y therapy.