Rj. Odonnell et al., RECURRENCE OF GIANT-CELL TUMORS OF THE LONG BONES AFTER CURETTAGE ANDPACKING WITH CEMENT, Journal of bone and joint surgery. American volume, 76A(12), 1994, pp. 1827-1833
The nine-year experience with sixty patients who had had a giant-cell
tumor of a long bone was reviewed to determine the rate of recurrence
after treatment with curettage and packing with polymethylmethacrylate
cement, The demographic characteristics, including the age and sex of
the patient and the site of the tumor, were similar to those that hav
e been reported for other large series. An average of four years (rang
e, two to ten years) after the operation, the over-all rate of initial
local recurrence was 25 per cent (fifteen of sixty patients). Patient
s who had had a tumor of the distal aspect of the radius had a higher
rate of recurrence (five of ten) than those who had had a tumor of the
proximal aspect of the tibia (seven [28 per cent] of twenty-five) or
of the distal part of the femur (three [13 per cent] of twenty-three).
Higher rates of recurrence were also noted for patients who had had a
pathological fracture (three of six), those who had had a Stage-III t
umor according to the classification of Campanacci et al, (six of sixt
een), and those who had not had adjuvant treatment with either a high-
speed burr or phenol (eight of nineteen). Patients who had had an init
ial recurrence after packing with cement had a low rate of secondary r
ecurrence when the initial recurrence had been treated with a wide res
ection or a second intralesional procedure (zero of ten and one of fiv
e patients, respectively), after an average of three years (range, ten
months to eight years). No patient had a multicentric tumor or metast
asis. This study demonstrates that curettage and packing with cement c
ompares favorably with traditional methods of intralesional treatment
of giant-cell tumors of the long bones in terms of the rate of initial
local recurrence. Furthermore, the effectiveness of treatment of a re
currence with either an intralesional or a wide excisional procedure d
oes not appear to be diminished by initial curettage and cementing.