LIPID-A AND RELATED-COMPOUNDS .29. SYNTHESIS OF BIOLOGICALLY-ACTIVE N-ACYLATED L-ASPARAGINE-CONTAINING D-GLUCOSAMINE DERIVATIVES STRUCTURALLY RELATED TO LIPID-A

Authors
SUHARA Y ARAKAWA M IKEDA K ACHIWA K
Citation
Y. Suhara et al., LIPID-A AND RELATED-COMPOUNDS .29. SYNTHESIS OF BIOLOGICALLY-ACTIVE N-ACYLATED L-ASPARAGINE-CONTAINING D-GLUCOSAMINE DERIVATIVES STRUCTURALLY RELATED TO LIPID-A, Chemical and Pharmaceutical Bulletin, 42(12), 1994, pp. 2526-2531
Citations number
27
Categorie Soggetti
Pharmacology & Pharmacy",Chemistry
Journal title
Chemical and Pharmaceutical Bulletin → ACNP
ISSN journal
00092363
Volume
42
Issue
12
Year of publication
1994
Pages
2526 - 2531
Database
ISI
SICI code
0009-2363(1994)42:12<2526:LAR.SO>2.0.ZU;2-Y
Abstract
New beta-N-acylated L-asparagine-linked D-glucosamine derivatives, in which the reducing unit of lipid A has been mimicked by a lipoamino ac id, have been synthesized. Compounds 1 and 2 exhibit mitogenicity and nitric oxide (NO) productivity.