B. Fraioli et al., TRANSMAXILLOSPHENOIDAL APPROACH TO TUMORS INVADING THE MEDIAL COMPARTMENT OF THE CAVERNOUS SINUS, Journal of neurosurgery, 82(1), 1995, pp. 63-69
A transmaxillosphenoidal approach was used to remove sellar tumors inv
ading the cavernous sinus. This procedure, a widening of the standard
transsphenoidal approach to the sella turcica, uses the sublabial or t
ransnasal route in which the medial wall of the maxillary sinus is lat
erally dislocated. This method provides good exposure of the prominenc
es of bone above the carotid artery which lies on the posterolateral w
all of the sphenoid sinus. This bone area is the key to opening the ca
vernous sinus inferomedially and removing lesions within its medial co
mpartment. The inferomedial approach takes an entirely extracerebral r
oute so that tumors invading the cavernous sinus through its medial wa
ll are approached inferomedially following the direction of tumor grow
th. It also allows direct visualization of the intracavernous carotid
artery during tumor removal, thus sparing the cranial nerves, which ru
n on the opposite side. Adequate surgical exposure of a pituitary aden
oma is achieved with a custom-made sphenoidal retractor with asymmetri
c blades, the shorter blade holding aside the thin medial wall of the
maxillary sinus. Between October, 1989, and July, 1993, 11 patients wi
th tumors invading the cavernous sinus underwent surgery via this appr
oach; 10 had pituitary adenomas and one had a craniopharyngioma. Eight
tumors were treated by primary operation: four tumors were totally an
d four subtotally (> 80%) removed; one tumor already operated on elsew
here was totally removed; and of two tumors already operated on and ir
radiated, one was subtotally removed and the other only partially (app
roximately 40%) removed owing to marked postirradiation scarring. None
of the patients suffered permanent cranial nerve deficit and all but
one showed marked clinical improvement.