A case of cerebral abscess caused by Fonsecaea pedrosoi is reported in
a nonimmunocompromised 15-year-old boy. In the absence of a primary c
utaneous lesion, this fungus was considered to be a primary neuropatho
gen. The fungus was cultured and characterized from the abscess materi
al obtained at surgery. Prompt therapy using amphotericin B and 5-fluc
ytosine helped in the successful recovery of this patient.