HORIZONTAL TRANSMISSION OF HEPATITIS-B VIRUS

Citation
P. Vandamme et al., HORIZONTAL TRANSMISSION OF HEPATITIS-B VIRUS, Lancet, 345(8941), 1995, pp. 27-29
Citations number
10
Categorie Soggetti
Medicine, General & Internal
Journal title
LancetACNP
ISSN journal
01406736
Volume
345
Issue
8941
Year of publication
1995
Pages
27 - 29
Database
ISI
SICI code
0140-6736(1995)345:8941<27:HTOHV>2.0.ZU;2-A
Abstract
In 1991-92, a cross-sectional survey in Flanders (Belgium) for hepatit is B virus (HBV) markers among 277 relatives of institutionalised ment ally handicapped persons to evaluate the prevalence of hepatitis B and the risk of infection showed that relatives of an HBV positive reside nt were 7.6 times more likely to be infected than relatives of an HBV seronegative mentally handicapped person. HBV infection among the fami ly members could be attributed in 83% to exposure to an HBV positive r esident. This study demonstrated the importance of horizontal transmis sion among relatives of institutionalised mentally handicapped people, even if family contact is reduced to weekend and holiday activities. We recommend that HBV vaccination policy should be expanded to include relatives of institutionalised mentally retarded people.