SYNTHESIS AND STRUCTURES OF PLATINUM(II) MIXED-LIGAND COMPLEXES WITH PURINE OR PYRIMIDINE-BASES OF DNA AND IMIDAZOLE DERIVATIVES .2.

Platinum(II) mixed ligand complexes with either purine or pyrimidine a nd imidazole derivatives were prepared and characterized by i.r., Rama n and electronic spectroscopy. The compounds had the general formula [ PtL(1)L(2)Cl(2)], where L(1) = adenine, guanine, hypoxanthine, cytosin e, 2-aminopyrimidine; L(2) = N-methylimidazole, N-ethylimidazole or N- propylimidazole. The platinum(II) complexes had a square planar struct ure with cts-halogens. Purine or pyrimidine and imidazole derivatived bases acted as monodentate ligands coordinated via the N(7) of purine and N(3) of pyrimidine and imidazole derivatives.