The effect of Super-EBA cement as a root-end filling placed in teeth b
efore replantation was examined in eight molar roots in monkeys. After
extraction, root ends were resected, the canals contaminated with ora
l bacteria, root-end cavities prepared, and fillings of Super-EBA plac
ed before replantation. After 8 wk, the jaws were removed and prepared
for histological examination. The tissue response to Super-EBA was ve
ry mild, with only a few inflammatory cells being observed at the root
end of 3 of the 8 roots filled. Previous work showed a similarly mild
response to Intermediate Restorative Material and a very much more se
vere response to amalgam. It is concluded that the tissue response to
Super-EBA as a root-end filling is acceptable and considerably more fa
vorable than that to amalgam.