K. Konya et al., INDOLE-DERIVATIVES AS POTENT INHIBITORS OF LARVAL SETTLEMENT BY THE BARNACLE, BALANUS AMPHITRITE, Bioscience, biotechnology, and biochemistry, 58(12), 1994, pp. 2178-2181
A potent inhibitor of larval settlement by the barnacle, Balanus amphi
trite, was isolated as 2,5,6-tribromo-1-methylgramine from a marine in
vertebrate. In comparative tests on the activity of related compounds,
such compounds as 2-methylgramine and 2-methyl-3-(morpholinomethyl)-i
ndole exhibited potent inhibitory activity. The inhibitory activity to
ward larval settlement was found not to be due to toxicity but to a re
pellent effect.