USE OF PT-191 RADIOTRACER FOR THE DEVELOPMENT OF ENRICHMENT PROCEDURES TO DETECT NATURAL LEVELS OF PLATINUM IN BIOLOGICAL AND ENVIRONMENTALMATERIALS

The Pt-191-radiotracer is a powerful tool to develop separation and pr econcentration methods for Pt. The radiotracer was produced either thr ough Pt-190 (n,gamma) Pt-191 reaction on Pt enriched in Pt-190, or thr ough Ir-191 (p,n) Pt-191 reaction on natural Ir, followed by Pt/Ir sep aration. The solvent extraction behavior of Pt-191(IV) from HCl with t ributylphosphate, rubeanic acid in tributylphosphate and thenoyltriflu oroacetone in n-butylalcohol/acetophenone, followed by back-extraction with 2 mol/L NH4OH was studied. The overall recovery from a biologica l matrix is up to 80%. Trace amounts of Pt-191 were also preconcentrat ed as bis-(carboxymethyl) dithiocarbamate chelates on an XAD-4 microco lumn and eluted with EtOH/1 mol/L HNO3. More than 80% is recovered in 2 mt or about 70% in 300 mu L.