Schistosoma mansoni cercariae have been shown to aggregate in the pres
ence of glass slides treated with clear nail varnish and linoleic acid
. In choice chambers cercariae move toward the stimulant, but this beh
avior is not seen when linoleic acid is omitted. After 30-45 min, the
cercariae were concentrated near the end of the choice-chamber contain
ing the linoleic acid slide. When the cercariae were added in the cent
er of the choice chamber, they formed a diffuse cloud that dispersed s
lowly in both directions in the absence of linoleic acid. Cercariae ag
gregating in the vicinity of a stimulant surface are not immediately s
timulated to commence penetration; this appears to be time and dose re
lated.