P. Bantz, PROPHYLACTIC ANTIBIOTICS IN THORACIC-SURG ERY, AIRWAY ENDOSCOPY, THORACIC TRAUMA AND LUNG TRANSPLANTATIONS, Annales francaises d'anesthesie et de reanimation, 13(5), 1994, pp. 73-77
Effectiveness of prophylactic antibiotics is at present time well docu
mented for many surgical procedures. In lung surgery, numerous randomi
zed double-blinded studies have demonstrated the effectiveness of 1st
or 2nd generation cephalosporins, administered over a short period of
time, not exceeding 24 h. In the opposite, thoracic injuries do not se
em to require prophylactic antibiotics, except penetrating injuries of
the chest, which could benefit from a single antibiotic injection. In
case of lung transplantation, infectious complications result from ma
ny factors, among which immunosuppression plays an important role. A p
rolonged antibiotherapy is routinely used by many transplantation team
s, despite the lack of studies proving the effectiveness of this pract
ice.