FIRST INTENTION 2-DRUG TREATMENT FOR HIGH BLOOD-PRESSURE

The limited efficacy of single-drug regimens in the treatment of high blood pressure has led to an evaluation of combination regimens for fi rst intention treatment. Two-drug regimens favor the hypotensive effic acy and reduce the frequency of certain side effects, Medications comb ining two drugs in a single formulation would allow use as first line treatment although marketing authorizations have not yet been obtained . In addition, current good clinical practice recommendations do not a llow combination therapy in this situation. A complete assessment base d on medical results and cost effectiveness will undoubtedly confirm t he usefulness of two-drug therapies as first line treatment for modera te hypertension.