It is shown in this paper that there are close connections between the
notion of D-stability of a real square matrix and several quantities
related to the structured singular value. As a main result, we show th
at a real square matrix is D-stable if and only if the real structured
singular value of some complex matrix is less than one. This conditio
n implies that checking D-stability may in general be an NP-hard probl
em. Since the exact verification of D-stability is difficult, we provi
de several additional conditions that are either necessary or sufficie
nt, and these conditions are also connected to the real or complex str
uctured singular values. These results are further extended to the not
ion of strong D-stability.