Wr. Panje et al., SURGICAL-MANAGEMENT OF THE HEAD AND NECK-CANCER PATIENT FOLLOWING CONCOMITANT MULTIMODALITY THERAPY, The Laryngoscope, 105(1), 1995, pp. 97-101
The simultaneous use of chemotherapy and radiotherapy (concomitant the
rapy) has exceptional promise in the treatment of head and neck cancer
. In this limited review, seven head and neck cancer patients who unde
rwent prior concomitant therapy and subsequent surgery developed wound
-healing complications that were delayed (22-day average) in onset. Pa
ranasal sinus and base of skull operations had less significant wound
morbidity than those cases requiring simultaneous transgression of the
neck and upper aerodigestive tract. The use of arterialized flaps did
not in itself prevent wound breakdown. The formation of controlled fi
stulae, delay of reconstruction, and avoidance of simultaneous neck an
d upper aerodigestive tract entry are important considerations in avoi
ding wound-healing complications after concomitant therapy. In this se
lect group of patients, surgery should be approached with extreme caut
ion and conservatism.