A patient suffering from persistent hoarseness was eventually shown to
have laryngeal leishmaniasis. The incubation period for the disease m
ust have been at least 16 years, following infection in Southern Europ
e. Mucosal leishmaniasis is rare in the Eastern hemisphere, and laryng
eal leishmaniasis has not previously been reported in the UK. Previous
Mediterranean cases have run a similar chronic course and have caused
diagnostic difficulty, in particular being mistaken for malignancy. T
reatment with aminosidine was ineffective, but the patient responded t
o liposomal amphotericin.