DETECTION OF OXYGEN-DERIVED RADICALS IN BIOLOGICAL-SYSTEMS USING ELECTRON-SPIN-RESONANCE

Authors
MASON RP HANNA PM BURKITT MJ KADIISKA MB
Citation
Rp. Mason et al., DETECTION OF OXYGEN-DERIVED RADICALS IN BIOLOGICAL-SYSTEMS USING ELECTRON-SPIN-RESONANCE, Environmental health perspectives, 102, 1994, pp. 33-36
Citations number
21
Categorie Soggetti
Public, Environmental & Occupation Heath","Environmental Sciences
Journal title
Environmental health perspectives → ACNP
ISSN journal
00916765
Volume
102
Year of publication
1994
Supplement
10
Pages
33 - 36
Database
ISI
SICI code
0091-6765(1994)102:<33:DOORIB>2.0.ZU;2-N
Abstract
Oxygen-centered radicals, particularly the hydroxyl and superoxide rad icals, have been postulated in many biochemical reactions and have bee n implicated in many adverse reactions in vivo. This article begins wi th a review of spin-trapping detection of oxygen-centered radicals in vitro and concludes with a presentation of our approach to the detecti on of the hydroxyl radicals in models of acute iron and copper poisoni ng.