OZONE, NO, AND NO2 - OXIDANT AIR-POLLUTANTS AND MORE

This article reviews the acute and chronic toxicity of the three oxida nt air pollutants ozone, nitric oxide (NO), and nitrogen dioxide (NO2) . The toxicity of binary mixtures of NO2 with other inhaled agents is also discussed. Newer studies are emphasized, especially those publish ed in the last 5 years or still in press. Very recent data from our la boratory that suggest a new cellular mechanism of importance in lung i njury in animals exposed to mixtures of ozone and NO2 that may have ge neral relevance with regard to the effects of oxidant air pollutants o n the lung are also presented.