ENANTIOSELECTIVE HYDROSILYLATION OF KETONES WITH A CHIRAL TITANOCENE CATALYST

Authors
CARTER MB SCHIOTT B GUTIERREZ A BUCHWALD SL
Citation
Mb. Carter et al., ENANTIOSELECTIVE HYDROSILYLATION OF KETONES WITH A CHIRAL TITANOCENE CATALYST, Journal of the American Chemical Society, 116(26), 1994, pp. 11667-11670
Citations number
50
Categorie Soggetti
Chemistry
Journal title
Journal of the American Chemical Society → ACNP
ISSN journal
00027863
Volume
116
Issue
26
Year of publication
1994
Pages
11667 - 11670
Database
ISI
SICI code
0002-7863(1994)116:26<11667:EHOKWA>2.0.ZU;2-B
Abstract
The first efficient asymmetric hydrosilylation of aromatic ketones wit h an early transition metal chiral catalyst affords alcohols with exce llent enantioselectivity. The reaction is general for aromatic ketones and exhibits a moderate degree of functional group compatibility.