A NEW FORM OF MANDIBULOFACIAL DYSOSTOSIS WITH MACROBLEPHARON AND MACROSTOMIA

We report on a girl aged 7 years with normal mental development but an unusual form of mandibulofacial dysostosis. The hallmarks of the synd rome are a round, flat face, severe hypertelorism, downslanting palpeb ral fissures extending to the temples, a broad nasal base, anteverted nares, small, posteriorly rotated ears, a long, smooth philtrum, a thi n upper lip, striking macrostomia, retrognathism with reduced height o f the mandible, and irregularly placed teeth, some of them missing.