AN EFFICIENT ROUTE TO ALPHA,BETA-EPOXY KETONES OF HIGH ENANTIOMERICALPURITY

Authors
PEGORIER L PETIT Y MAMBU A LARCHEVEQUE M
Citation
L. Pegorier et al., AN EFFICIENT ROUTE TO ALPHA,BETA-EPOXY KETONES OF HIGH ENANTIOMERICALPURITY, Synthesis, (12), 1994, pp. 1403-1405
Citations number
14
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Synthesis → ACNP
ISSN journal
00397881
Issue
12
Year of publication
1994
Pages
1403 - 1405
Database
ISI
SICI code
0039-7881(1994):12<1403:AERTAK>2.0.ZU;2-A
Abstract
Acylepoxides were obtained in high enantiomeric purity (ee = 92-99%) b y addition of organolithium or Grignard reagents to enantiomerically p ure methyl or ethyl 2,3-epoxypropanoates at low temperature (- 85 degr ees C).