IMPROVED SYNTHESIS OF CHIRAL N-PROTECTED ALLYLIC AMINES

Authors
WEI ZY KNAUS EE
Citation
Zy. Wei et Ee. Knaus, IMPROVED SYNTHESIS OF CHIRAL N-PROTECTED ALLYLIC AMINES, Synthesis, (12), 1994, pp. 1463-1466
Citations number
22
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Synthesis → ACNP
ISSN journal
00397881
Issue
12
Year of publication
1994
Pages
1463 - 1466
Database
ISI
SICI code
0039-7881(1994):12<1463:ISOCNA>2.0.ZU;2-D
Abstract
The alpha-ester group of N-protected alpha-amino esters was reduced wi th diisobutylaluminum hydride to an intermediate aluminoxy acetal that on reaction with a Wittig reagent afforded the title chiral compounds in 48-78 % chemical yields.