IDENTIFICATION OF MULTIPLE TRANSCRIBED SEQUENCES FROM THE SPINAL MUSCULAR-ATROPHY REGION ON HUMAN-CHROMOSOME-5

Authors
PIZZUTI A COLOSIMO A RATTI A CAPON F GENNARELLI M SILANI V GHEZZI C LOCICERO S CALABRESE G PALKA G SCARLATO G NOVELLI G DALLAPICCOLA B
Citation
A. Pizzuti et al., IDENTIFICATION OF MULTIPLE TRANSCRIBED SEQUENCES FROM THE SPINAL MUSCULAR-ATROPHY REGION ON HUMAN-CHROMOSOME-5, Biochemical and biophysical research communications, 206(1), 1995, pp. 294-301
Citations number
16
Categorie Soggetti
Biology,Biophysics
Journal title
Biochemical and biophysical research communications → ACNP
ISSN journal
0006291X
Volume
206
Issue
1
Year of publication
1995
Pages
294 - 301
Database
ISI
SICI code
0006-291X(1995)206:1<294:IOMTSF>2.0.ZU;2-I
Abstract
We report the isolation and characterization of novel expressed sequen ces from the spinal muscular atrophy (SMA) region on human chromosome 5q13. Based on the sequence homology studies these cDNAs were grouped in four classes, one of which shows extensive homologies with the beta -glucuronidase (BG) gene, differing in exon arrangement. The other cDN As do not show any strong homology with known DNA sequences. (C) 1995 Academic Press, Inc.