J. Stachura et al., DISPERSED AND ACINAR FORMS OF PANCREATIC METAPLASIA IN HUMAN GASTRIC-MUCOSA, Folia histochemica et cytobiologica, 32(4), 1994, pp. 251-255
Pancreatic acinar cell metaplasia of the gastric mucosa is a newly rec
ognized entity. Its physiological relevance and association with other
gastric pathological conditions remains to be elucidated. We studied
morphology of pancreatic metaplasia of the gastric mucosa in 15 cases.
Two morphological forms of pancreatic metaplasia were noticed: an aci
nar form and a diffuse form. The diffuse form is characterized by smal
l foci of pancreatic metaplasia dispersed in the gastric mucosa withou
t any separation from the surrounding gastric glands. The acinar form
is characterized by acini of pancreatic metaplasia separated from the
surrounding gastric mucosa by strands of connective tissue and single
smooth muscle cells. Acinar form of pancreatic metaplasia seems to be
spared by the chronic atrophic gastritis involving the neighboring gas
tric mucosa.