COMPUTER-TECHNOLOGY OF GENOGEOGRAPHIC ANA LYSIS OF A GENE POOL .2. STATISTICAL TRANSFORMATION OF MAPS

Citation
Ev. Balanovskaya et al., COMPUTER-TECHNOLOGY OF GENOGEOGRAPHIC ANA LYSIS OF A GENE POOL .2. STATISTICAL TRANSFORMATION OF MAPS, Genetika, 30(11), 1994, pp. 1538-1555
Citations number
15
Categorie Soggetti
Genetics & Heredity
Journal title
ISSN journal
00166758
Volume
30
Issue
11
Year of publication
1994
Pages
1538 - 1555
Database
ISI
SICI code
0016-6758(1994)30:11<1538:COGALO>2.0.ZU;2-J
Abstract
Transformations of computer maps of geographical distribution of gene frequencies using basic mathematical statistical procedures are consid ered. These transformations are designated as statistical transformati on of maps. Two transformation groups are considered: of one map separ ately and of a group of maps. Transformations possess a value beyond t heir use as intermediate stages of more complicated cartographical ana lysis: the resulting maps carry entirely new information on the geogra phy of genes or a gene pool. This article considers three examples of obtaining new genetic profiles using statistical transformation algori thms. These profiles ar of: heterozygosity (of HLA-A,B,C loci in north eastern Eurasia); (2) disease risk (Rh-incompatibility of mother and c hild with simultaneous registration of Rh and ABO blood groups in East ern Europe); (3) genetic distances (from own mean ethnic values for Be larus' and from mean Russian values for the gene pool of Eastern Europ e).