Ey. Artamonova et al., DIFFERENCES IN ANTIMUTAGENIC ACTIVITY OF VITAMINS IN HUMAN-CELLS AFTER EXPOSURE TO MUTAGENS OF DIFFERENT NATURE, Genetika, 30(11), 1994, pp. 1556-1557
The effect of ascorbic acid, retinol, and their mixture on the surviva
l of human cells treated by mutagens was studied. The results provide
evidence about the specific protective activity of each vitamin with r
espect to specific mutagenic effect. Information about specificity of
''antimutagen-mutagen'' effect accounting for mutagen cytotoxic proper
ties can be readily obtained with the use of the method of vital cell
staining with Tripane Blue.